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1.
JMJ-Jamahiriya Medical Journal. 2008; 8 (1): 39-43
in English | IMEMR | ID: emr-87671

ABSTRACT

The current analysis was undertaken to determine the effect of Nd: YAG laser in treatment of different stages of periampullary tumours, whether benign or malignant. Patients, In a retrospective study of 26 patients with a histological diagnosis of primary periampullary adenocarcinoma [8 patients], metastatic adenocrcinoma into periampullary region [8 patients] and adenoma with or without dysplasia [10 patients] which were classified into 3 groups A, B and C respectively. All patients treated in two main hospitals in Glasgow between 1988 and 1998, with Nd: YAG laser with different number of sessions [1-8], without any major complications. Group A, treatment was successful in ablating and relieving symptoms in 5 patients but failed in 3 patients. Group B, Nd: YAG laser succeeded to relieve symptoms but not increase survival, [median survival time was 5 months]. Group C, Nd: YAG Laser succeeded in relieving symptoms in all ten patients and completely ablated the tumour in most of them 9/10, median survival time 60 months. Nd: YAG laser appears to be an effective treatment for benign and early malignant primary periampullary tumours as well as for the palliation of advanced malignant tumours with the main advantages it can be used in patients unfit for surgery and it is associated with less complications than other surgical procedures. Although these results are encouraging, the sample is relatively small and further follow up is required in order to recommend Nd: YAG laser photoablation as additive modalities for these patients


Subject(s)
Humans , Male , Female , Ampulla of Vater/pathology , Common Bile Duct Neoplasms/therapy , Duodenal Neoplasms/therapy , Laser Therapy , Retrospective Studies , Palliative Care , Adenocarcinoma , Adenoma
2.
LMJ-Lebanese Medical Journal. 1995; 43 (4): 200-207
in English | IMEMR | ID: emr-122010
3.
An. Fac. Cienc. Méd. (Asunción) ; 20(1/2): 17-51, 1988. ilus, tab
Article in Spanish | LILACS | ID: lil-85276

ABSTRACT

Desde noviembre de 1981 a marzo de 1988 se han realizado 200 esfinterotomías endoscópicas en pacientes de diversos centros hospitalarios. En relación al sexo, 131 casos (70%) correspondió al sexo femenino y 64 pacientes (30%) al sexo masculino. Las edades oscilaron lugar entre las indicaciones benignas (41,5%), seguido de la litiasis del coledoco con vesícula litiásica "in situ" (43%), pancreatitis aguda biliar (8.5%), fibrosis del Oddi (4%) y en el 0.5% la litiasis autóctona del coledoco. Las indicaciones se ampliaron en casos de lesiones malignas como tumores ampulares (6.5%) y bilio-pancreáticos en el 6%. La extracción de los cálculos coledocianos fue espontánea en el 6.5% e instrumental (Dormia-fogarty) en el 85.7%. Se ha tenido un 7.7% de litiasis residual post-esfinterotomía, casos que fueron tratados con la instalación de la sonda naso-biliar como medida pre-operatoria. Un método paliativo en los casos de carcinoma ampular y biliopancreático, fue la combinación de la esfinterotomía endoscópica con la coloración de prótesis transpapilar y ha ganalo un lugar preponderante en el manejo de estas patologías. La morbilidad fue del 1.5% entre las que se mencionam la hemorragia, colangitis y pancreatitis. La mortalidad fue del 0.5% y la efectividad global del método fue del 91%


Subject(s)
Adolescent , Adult , Middle Aged , Humans , Male , Female , Common Bile Duct Diseases/therapy , Sphincterotomy, Transduodenal , Ampulla of Vater , Cholangiopancreatography, Endoscopic Retrograde , Common Bile Duct Neoplasms/therapy , Common Bile Duct Diseases , Pancreatitis/therapy , Retrospective Studies
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